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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48b973494156e8148ce0a7bbf6199303cc66b2470f83b83f62130833eacea3b' 
  AND token = 'Sf+B/ZYJ15s+JmgF4/pz4xWReVgzYElrF4mE7S7QPrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}