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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e280210e15b858271f124c79df2133c421256ebd9a937b4e54202777ccfbed07' 
  AND token = 'YgbyAbdEsB6uhfjXuFbJ14KD3lKVoDSxQRD6cWGcytk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}