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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2e1c40cfd2ace376a61c907e9f28446bca7b3cbf43c53289849c815f2a247aa' 
  AND token = 'MprLdpj9tOgF9UiWXnP77uvqCF1Gobg5wUYnOwFzezw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}