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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99a21a51733af938787d9bd4145edf44cfcfc4030f7e477324b74397e3b57884' 
  AND token = 'vx+pSeURmqO4enFMgWgZCbBXt6IfeYjtC83iDUH2Kew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}