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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65687e38f33f055c7402c5e5b0561365c75dd7f4fd81ece2473d520052b7990' 
  AND token = 'kvBit46oA1JZvuMUzHrXzy1cTaEUFQhs1DNVOLUIido=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}