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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '455748af57d73d24200bd56ebf9e7f5a6b3a41a08d680a801ea8488b57739ea1' 
  AND token = 'BDr5Y/x4TQf0qzJZS12//L6wHFxRkoHxBSWMrJ7Ko+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}