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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2431ed12bbe7f49e453090bc5bc7a7f315af361365a68be0e19c98730e6ca4f' 
  AND token = '4zyFSO1DClZi4ORGyY4dY/0uf3gr8tyH7Xp5jjuFat0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}