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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '397cf5771ec660050fc80b630b0632803bb0b58d415fdb1cfcc698a7091add36' 
  AND token = 'l/IVhHfeUrB4WGEjzQZZUcarwUbVKzit1qcff+5tcYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}