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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04af95d2ef6f540c6716877b9b9af5d8c7da71360967b12ad5ce4afd6398c718' 
  AND token = 'R68vLWg8kIElnGzDFZWRC2aZ/Ks0ywZ0OBYg1cB107c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}