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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800e64fa67b389348de6f23bd270539f86c2a3cfb64d24f21bfdcc3c1a85e95d' 
  AND token = 'G4sV4ImqsgVTiNBIWT5HFtsTlKtL7n3nc+r6oiZcCxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}