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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b526287de5f3603b7a5370770be8644f28da66cf78589e6cf0e620c672db208d' 
  AND token = '7/7NGtg5TvWNqlypLJWsKpbJe3MEP9WYdJhERlgWTo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}