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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3fc2210b5d744bb9b3a200037386ec99f7a2809736f5b75a55d206c96d4f4d6' 
  AND token = 'LDUEwFB1XfpyBbxnCUD70kbPYknzfX5mXZVOt45qEFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}