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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '595b53919eee4c5090c350a7a35acb88be6427aac68733e9c835d7d65d894881' 
  AND token = 'W4dlQmhBaAFi90q+1d52Pnh4WG/xx0KgQUyKEMSw9wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}