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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e164353df0934abd8de63a51d70a6543b20b262e9d8715e9b347b2eae06346ef' 
  AND token = 'IDCyYUuzWJaEwf6NItqzuIkHXIrFEI3rvmpi3i9NxaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}