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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1654b1516b489930f80132f009864bd0420bd4f03a820335207b57365fcee96e' 
  AND token = 'ClWHGf9YnXeMLc70RkNrk4slyut7YFvDqpsGWvAl8co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}