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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b7338c5d7c2c185d388bf143954ed8a3a218a63dd63878a0fa5d6db87e30ad9' 
  AND token = 'v0wDpxzNSA8CQFoRMnRntZDF/cjZeGFKHwM6qF5WjDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}