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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7953433b0503fac23e0b38ef491273d976ff4734401cecc20747ca38df4cbf6a' 
  AND token = 'twoYH8LKgtEnQhMwPe01NeiHhqVKAf4knQSrm/qFXcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}