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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0621caeb21e5b3e43b11dfaf199c1d854494d285c89dbe254d4cabada9b25c0' 
  AND token = 'bvO9269GgeuMp+zCLujl7Z7oN3+mdn/BvEHm1tEEz8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}