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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627259d25d36da1e5313d2ab41cebb1936e178de101b6a71e325f776fc674b21' 
  AND token = 'OxExRGzXvoFtuu/+55GW/1Z+mMO0BD9rlbPpXpunKB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}