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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280fbefd6bc0c0e66d24b3a04ac7fd781fd27cbd603f36cfa92ce61ef464646b' 
  AND token = 'kqSl2i1lriyw/W6dhfd7JxJFK6tDWR4hgAsTN60G2CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}