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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1468f6a23c52b7f551f838bcf9619d7d56dad32ec1bb12c80f0923f56a33a5f2' 
  AND token = 'V3dD8yOf+vaiI++KpVT3i8/boFS3u5QTDJNdxxIT9K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}