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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b21da43caa4628bfe9e32a6ab3934e393074b16232cd2929f3c1d09ad8ac5149' 
  AND token = 'VSuxG4N3YtnJfBVY90sOGA2IaOvk1unFud8mRulQBpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}