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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2345224193d87f5051e1461fd5ce784a72800d957525949174157a032288b2e5' 
  AND token = 'gJy0xvPjzaG3zgjH0KfvFJvfl2GKm9Nj6WmG9yIzf1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}