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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40f09d7b0d2c88a7b55fe801d0fb55224fc9c9b5ed7fa8b61ac1dd8fc79bbe23' 
  AND token = 'sF5AIkQeWJKm5cJfQVceIyZrycb5ftC6+cd8wvcMqt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}