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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738b53e2f6aed0d124c11e6fea0b2aa0ed087520888393b065cec77c15c9c5fa' 
  AND token = 'pJhDwR7ibpRTmxqllrYN5fkD0NqTWzEDaL1PjGgcQY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}