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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a17ab70ba1481b21264c6cbb31a949ae4f7961af87ed4231b6a158c3c1081347' 
  AND token = 'vopiaX/4+IiDQv767OhGjyQWxalGMnHby4Kw9AmMg4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}