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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9de6d1bafdbf5fb46c71d621bbc8111cb85bd810c2fa404108f978e9c59d47a' 
  AND token = 'VLcRdMUiB5U6IYVyzGEtgEBZFWLhVMYQwylZZLCO3aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}