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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd107bbe772b46893c8264ad7d54dedd11aeb3913647d229d5ba5859bdab454df' 
  AND token = 'w0c0OZgXcKPjeXkiuLf+0Dem1As/MPsUwBNj2bklOj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}