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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880d65644398c36afe72912eccd258f12cd51d3bb005afd7ef00b37ca021adc0' 
  AND token = 'BfbSfU2uCZxUrQMXrggVROVHSBe6bgYI+4kwdxO1f9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}