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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa4d2e8db23bd73ead24e184422d012db33e656f4cbfdac84cd6ada64225e275' 
  AND token = 'NMH6UITZAz3g/mwXUw6rBc7T3u03yhfawjX2YcrWJDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}