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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a1a3cad1da3f1d2e02c124578e7889197e396b602e455dd75b4ef542bd34986' 
  AND token = 'DB3FsKMkMwbqWyEYD/1B8FhPkBMemRWAY3C+G0u/rPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}