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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43128680e316cc329f06ca17db2397ec26d7ab363a39c3f38a552387534d3e90' 
  AND token = 'D9Igfl3TC/tO9EaHupjQ1lpRxAh/bjE22fZNaO4jTAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}