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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1981bad2248bf6dcb5751cd8184b11532785e2d047a2a53b90b85515fb0cb326' 
  AND token = '1Tkoll5CragI0h2B8uOnSFnfYknEkh8ygCmBQGw/CSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}