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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51450d13f0b9d125fa55006b656a3da63649975fa5e68621e4ba4d7ee7a9484' 
  AND token = 'eENG+HocSSAM0KLXKPnT8DUYsKVepevbVHvidGVpe0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}