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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20ec10584c853464dd8d770f31c0c20141c27fe81713085a8612d75ebb31016f' 
  AND token = 'gf9YUHNFf0BSjvlRtX7g4p+xWlhYZw0X4GG72jHwn1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}