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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7607b90a5022cd0e2a403d960cb7778304716cf6def6d74bee1c1546109f8b2e' 
  AND token = '1Qq8/OrYGH1SgnZFaylv3D6uy2VvlkTTW8PiCNDUXK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}