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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2525402b73c7fb01db8d543124f4e09a272a6742513a18d5a7a577a47a6ed6' 
  AND token = 'iTEx2r1rUNELiW1Q3A+IgL7e5OXBmpi9PbuLznO5GsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}