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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c22ef33b8f1bd90a9f79e9de98c1d2b75f4aab59437cbe5408bc2520beb0fca' 
  AND token = '5lg8jx45+XVAsQkTZSCCg/HQ1BDkJRcrr0AL7+fB3HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}