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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51ac56eb521412c80e5c3fa2f661ec21c4806e26a8288d79f58a196833069e2' 
  AND token = '8+74pZa+p4pm+8KOmSH08PeMBS1PFJGuzCJ/z2ys7FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}