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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c3257abfbb0ed3e8a32632d0dfeac8cc77e1c1d6660abd63d0969b33fca307' 
  AND token = 'xTfUew81N0TyysidIcmNsG7mrB/zJIBlQrq/VIa7SmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}