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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49c5ffad92b23051a67f7ffda6a3fd2a3c49827fe383464c2a0f4a903f53b7d' 
  AND token = 'p0CSskddtoNAV5x0mG5zaqOWrdi2UfyRwdzVLpz3SVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}