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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd56d3b0c7e0a9a48da9d334fd34cf933441ee35db6c37f27af0d613c2f2d6253' 
  AND token = 'w3GKMFkqVtOzo13jDWTedaEanZ2pOaaPR2/8fDtw9GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}