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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3b6229e42612fe55b3b13595ff1fd4ea759a8e83b713754849378126b13ed4' 
  AND token = 'Y9jyBf3eIPdSerXErB6NfOL98vz5z66O1uWYc27ClCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}