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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68a2398ec76101089e1ccb61a1124945c4e40ce16320998a9d4680d0d63f24da' 
  AND token = 'SkWYmANxmOT3+xdX7ovcNATHxWE6bPWkOmbQ5m/GNLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}