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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b456c8957154131cb755ffc05c65089ac44e3c4b7d931f8fef71ffdfe7feefe1' 
  AND token = 'JMDyB9tZAahmIiI1iD+Ay50ASqlcNZ1nrX4Ny9CiByc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}