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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '871846b33e382f5c8469b414ad5b08a75a8d76d3b09d3469e204b02b4eee0f2a' 
  AND token = 'DpnnUd2/pttZpeCRFY1UANQmwnHB+xb3oVWkHd5HSN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}