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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '558b4b0b64183a4519d9188b49cf187ea3b813e2fe93141c811139431e5eb49b' 
  AND token = 'k9OIHTo2olwS5yLUd7Fxv7O8vcr+36Kc3rh4VjXVYTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}