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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66c935bcfeb6cede9e6aad010695c19890a1a1a70f7e10a30f9811e02bb7527' 
  AND token = 'eBXU2IFgteD3uvVUWgh3Re96fYNaMmW9l+8qfZW3jnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}