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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5509a61fe20c7ff6b62469d3e811abaf73c61e45d3527c4ca05343aa495e23' 
  AND token = 'HIR/Agr6tBRrxIkV5blsVaYBISvmvUbb4xHMwmP3Fp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}