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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecaeb1e28a592b27f92f3b1e76d38c6a321511a43ece3fbacc30243a5008a3f7' 
  AND token = 'bi/IUnx5nEfJS+7lcT9/mr/zXC/tmJjYKOsFn1bBlTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}